The content of this article is from the book “The Comprehensive Guide to Glutathione”
by Dr. Jimmy Gutman MD
Addiction is now considered a brain disease in which distinct biochemical
and physiological processes change brain structure and function.
Addiction is characterized by chronic, repetitive, compulsive behavior,
including drug abuse, gambling even shopping and sex-all with potentially
disastrous results. Patients are compelled to continue this behavior, even when they
understand the negative consequences.
Many addictive conditions have demonstrated similar biochemical changes
including lowered glutathione metabolism and increased oxidative stress. Examples
include compulsive gambling, as well as abuse of cannabis(marijuana),cocaine,
amphetamine, and nicotine (tobacco) released with each puff of smoke, wreaking
havoc in the lungs and airways, often leading to lung disease and cancer. In 2015 Prado et al
showed significant differences between NAC and a placebo group in both cigarette
consumption and exhalation of carbon monoxide gas. Although only a few small
studies looked specifically at smoking from the addictive perspective, early indications
suggest that larger trials are warranted.