What is the common denominator with all these conditions: Lupus, myasthenia gravis, chronic fatigue syndrome, rheumatoid arthritis, fibromyalgia, multiple sclerosis, polymyositis, scleroderma, ALS , grave’s disease, sarcoidosis, crohn’s disease?
ANSWER: GLUTATHIONE DEFICIENCY
The immune system coordinates a variety of specialized cells to fight off infection and other threats. The healthy growth and activity of these cells depends upon the availability of glutathione. Glutathione is at the heart of most immune functions, explaining why low levels are seen in many diseases. This is best exemplified by AIDS, which is characterized by a severely compromised immune system.
Raising and maintaining glutathione levels can minimize the risk of these diseases. Although only very ill people are severely deficient in glutathione, those in good or fair health will benefit from glutathione supplementation, especially considering the environmental toxins and drug-resistant bacteria we’re exposed to these days.
The use of glutathione supplementation fights all kind of diseases from respiratory to auto immune to degenerative diseases.
Without question, the best type of preventive medicine is an optimized immune system, and a critical means to optimize it is by feeding it glutathione. Glutathione as a dietary supplement.
We must first clarify an important, frequently misunderstood part of the glutathione story.
Upon learning about glutathione for the first time, many people go to their health store, buy it, and start dosing themselves. However, while glutathione is freely available in this form, this sort of oral, ingested glutathione will have negligible effects on your health. The product decomposes rapidly in the digestive system and is quickly removed from the gut. Apart from a few very specific instances, glutathione cannot be introduced into the body in this way. It must be made within your cells which is where it’s naturally found. The effective way to stimulate the production of glutathione is to provide your body with the basic elements it needs to make glutathione by itself. Some pharmaceutical medications, such as N-acetyl- cysteine (NAC), have been developed to provide these precursors. There are also natural ways to increase glutathione levels, in particular the use of denatured (bioactive) whey proteins. These are discussed throughout this website.
Breakthrough in cell defense.
Glutathione is heralded as a breakthrough in cell defense due to its immune-boosting capabilities. It does this function well since it is a high caliber antioxidant that not only neutralizes free radicals but also recycles other antioxidants. Remember, antioxidants are your defense against oxidative stress and the damage it brings in terms of disease and aging. This helps your immune system fight infections.
But glutathione does more than that.
Its presence in your lymphoid cells allows your immune system to work at its best. How so? Well, your immune system’s health depends on the presence of T cells. T cells, which are types of white blood cells, are the ones that determine how your body responds to foreign substances or antigens. If you have an infection, the T cell binds to the infected cell and kills it.
Here’s the thing.
T cells can only be cloned sufficiently when there are large quantities of glutathione in your body. Glutathione does the vital job of regulating T-cell proliferation, degradation, internalization and binding. It effectively increases the number of cellular binding receptors leading to more T cell production. This boosts your immune system and keeps it ready to fight against disease.
Thus, by its antioxidant and immune-enhancing function, glutathione proves itself to be a vital antioxidant, ready to heal and protect the body. But its importance does not stop there. It also plays the function of a detoxifier. And this function, like the other two, is also vital to relieving pain and guarding your body against disease.
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The content of this article is from the book “The Comprehensive Guide to Glutathione”
by Dr. Jimmy Gutman MD FACEP
Your body responds to such foreign substances by initiating a defense mechanism known as inflammation. During this action, the white blood cells release some chemicals that head over to protect your body from invaders.
When the chemicals are released, the blood flow to the affected area increases, and as a result, you may experience some warmth and redness. You may also experience some pain if the chemicals leak into your tissues. The more foreign substances your body takes in, the more your body strives to fight them. This may lead to chronic inflammation, which causes more harm than good as the body turns to attack itself.
The best thing you can do to give your body relief is to flush out the toxins. This is done by the use of a detoxifying agent.
This is where glutathione comes in.
Glutathione is the utmost detoxifying agent. The first thing it does is get rid of the harmful toxins known as free radicals. As you’ve already seen, free radicals wreak havoc by stealing molecules from healthy cells, thus, damaging such cells. But there’s something you need to keep in mind. Free radicals are just some of the toxins in your body. There are other toxins such as metabolic waste, heavy metals and lipid peroxides that your body still needs to eliminate.
Glutathione eliminates such toxins via a mechanism known as conjugation. This is where glutathione binds itself to the toxin at a specific site and makes it water-soluble. This neutralizes the toxin and enables it to be easily secreted from your body.
If you look at glutathione closely, you’ll notice that it does 3 important things as far as the detoxification process is concerned. First, it neutralizes free radicals. Second, it helps other cells neutralize free radicals by recycling them and third, it neutralizes other toxins in your body. All these roles make it possible for your body to function properly.
The liver, which is the largest organ in your body and the main detoxification organ, contains the highest concentration of glutathione. When glutathione levels are low, liver function is also affected. This results in large quantities of toxins in your body since such toxins cannot be eliminated successfully if your liver function is impaired. Thus, for your own good, it is vital that you have enough glutathione in your body so that your liver can carry out its detoxification function properly.
But here’s the thing.
Glutathione is produced by your body. It is something that comes from within and unfortunately, many people lack the enzyme that leads to the production of glutathione. Also, when it comes to detoxification, glutathione is quickly depleted especially during the first phase of detoxification. Thus, if you have it but it is not enough, your body will not be able to detoxify as it should.
Thus, in order to successfully detoxify your body and get rid of harmful toxins that cause disease, it is imperative that you raise your levels of glutathione. So what can you do to increase your glutathione levels? Are there specific things you can do?
“If glutathione is manufactured within the body, what can we do to maintain or increase glutathione levels? Some pharmaceutical drugs can do it, and so can some natural sources. Eating glutathione cannot. There are many ideas about how to raise glutathione levels in the body but only a few actually work — and some of them have side effects.
Glutathione is a tripeptide — a protein made up of three amino acids — in this case, glycine, glutamate (glutamic acid), and cysteine. The chemical structure of glutathione does not easily survive the digestive process, so eating it will not raise glutathione levels.
The building blocks (precursors) glutamate, cysteine and glycine from any source must be in a form that can be transported from the mouth, through the digestive system, into the blood and finally through the cell wall. Once there, the cell combines them into glutathione. Glutamate is derived from food sources containing uncooked glutamic acid, glutamine and glutamate. It is found in undenatured whey protein. Cysteine comes from such protein sources as eggs, raw milk, undenatured whey protein and in small amounts from other foods. The amino acid methionine can break down into cysteine. Various pharmaceutical drugs serve as cysteine delivery systems. Glycine is found in foods rich in the amino acids choline, glycine, serine and threonine. Only when the three precursors glutamate, cysteine and glycine are absorbed by the body and have passed through the wall of individual cells can the body manufacture glutathione.
Drugs like NAC and OTC can raise glutathione levels, but their effects are short-lived. These pharmaceutical drugs also have little nutritional value. Whey proteins have excellent nutritional value but usually lack glutathione precursors. The ideal source of dietary cysteine should be natural, nutritional, bioactive, and undenatured and As many of you are aware, whey protein, especially whey protein isolates (over 90% protein), are sometimes referred to as the “perfect” proteins because they contain all the essential amino acids required for your body’s protein synthesis. With a biological value (BV) of over 110, it would be challenging to find a protein utilized more efficiently than Immunocal.