Multiple Sclerosis

Click on the picture below to watch about the science of glutathione:

The content of this article is from the book “The Comprehensive Guide to Glutathione”
by Dr. Jimmy Gutman MD FACEP

The immune system coordinates a variety of specialized cells to fight off infection and other threats. The healthy growth and activity of these cells depends upon the availability of glutathione. Glutathione is at the heart of most immune functions, explaining why low levels are seen in many diseases. This is best exemplified by AIDS, which is characterized by a severely compromised immune system. 

Raising and maintaining glutathione levels can minimize the risk of these diseases. Although only very ill people are severely deficient in glutathione, those in good or fair health will benefit from glutathione supplementation, especially considering the environmental toxins and

drug-resistant bacteria we’re exposed to these days. 

The use of glutathione supplementation fights all kind of diseases from respiratory to auto immune to degenerative diseases.

Without question, the best type of preventive medicine is an optimized immune system, and a critical means to optimize it is by feeding it glutathione.

MULTIPLE SCLEROSIS

By Jimmy Gutman, MD, FACEP, McGill Univ. from his book “Glutathione,

Your Body’s Most Powerful Protector

Multiple sclerosis (MS) has in recent times been referred to as “the great crippler of young adults”.  It usually strikes victims in the prime of their life and is one of the most dreaded degenerative diseases of the nervous system.  The symptoms of MS are quite variable, ranging from one or two attacks of weakness in a limb or blurred vision, to a relentless, progressive deterioration of speech, movement and other basic functions.

MS affects various parts of the nervous system by destroying myelin, a fatty sheath that insulates nerve fibers rather as a plastic sheath insulates electrical wire.  This destruction leaves scars or plaques that short-circuit the electrical signals passing through the nerve fibers.  The scarring process is called sclerosis. 

Depending on the location of the nerves affected, patients may suffer localized weakness or stiffness, visual difficulties, diminished bladder or bowel control and other neurological dysfunctions.  Attacks may be mild, lasting only days and followed by remission, but most sufferers relapse after months or years.  A few experience rapid progression of the disease and are quickly disabled.

The causes of MS are still unclear.  However, many theories have been put forward.  Some point to environmental and/or genetic factors, and some researchers believe that certain viruses may be involved, or view MS as an autoimmune ailment (in which the immune system mistakenly attacks healthy tissue).  Others are investigating dietary factors or exposure to toxins such as lead, mercury, pesticides and carbon monoxide.  Yet another theory considers the role of allergies.

Conventional medicine treats the symptoms of MS but cannot cure it.  However, some newer drugs show promise in diminishing the rate of relapse.  Diets of all sorts have been widely tested without consistent results.  Everything about this disease is difficult to study because symptoms vary so widely, patients often recover spontaneously and one can never be sure whether or not a treatment has been instrumental.

Multiple sclerosis is one of a group of nervous system diseases called neurodegenerative disorders.  This group also includes Alzheimer’s, Parkinson’s and ALS (amyotrophic lateral sclerosis or Lou Gehrig’s disease).  Although the specific causes of these diseases are unknown, a number of recent studies suggest that an important role is played by oxygen-derived free radical formation and/or lack of adequate antioxidant defenses.

OXIDATION AND MULTIPLE SCLEROSIS

The myelin sheaths destroyed by MS are made of lipids, fatty substances highly sensitive to damage by lipid peroxidation, a particularly aggressive type of oxidation.  Our key metabolic defenses are glutathione and SOD (super-oxide dismutase).  It has been shown that elevating these natural defense systems reduces the damage of oxidative stress.

Investigations looking specifically at the breakdown products of oxidation have revealed significantly higher levels in MS patients.  Pradlip Toshniwal and Edwin Zarling from Loyola University in Chicago went one step further in their studies.  They were able to show that these levels of oxidative stress corresponded to the severity of the MS attack.

Some authors including S.M. LeVine from the University of Kansas suggest that the pathological process leading to the demyelination of nerves is possible because the immune system cooperates with a free radical generating system present within the myelin sheaths.  This explanation combines the two hypotheses that describe MS – that it is an autoimmune disease, and is also caused by oxidative stress.  He describes how during a demyelination episode, macrophages (cells of the immune system that are supposed to act protectively) seek out myelin and release powerful chemicals (lipases, proteinases, H202 and others).  These biochemicals result in tremendous levels of oxidative stress.

Such a hypothesis leads us to believe that either blunting the immune response or minimizing oxidative stress could help MS patients.  Immunosuppressive drugs that blunt the immune response have had only limited success.  This has driven researchers to find ways to improve antioxidant protection, glutathione modulation being one of the most promising areas.

GLUTATHIONE AND MULTIPLE SCLEROSIS

Many studies have compared groups of MS patients to healthy individuals.  Among other things, they have measured levels of reactive metabolites (breakdown products of oxidation) and of protective enzymes, especially glutathione .

An Italian group headed by Vince Calabrese drew samples of cerebrospinal fluid (CSF) through spinal taps.  CSF analysis is a good indicator of brain metabolism.  They found that glutathione -peroxidase levels in the cerebrospinal fluid of MS patients were consistently low.  Their conclusion was that in MS, the fundamental activity of anti-oxidation is abnormal and that oxidative stress plays a causative role.

Another study looking at CSF was performed by the Swedes G. Ronquist and G. Frithz who tested spinal taps from a large number of patients including those with stroke, seizures, brain tumors and MS.  The cerebrospinal fluid of MS patients were found to be almost entirely lacking in glutathione .

There is further evidence of the involvement of free radical elevation and GSH depletion in MS.  Helen Langemann in Switzerland measured glutathione levels within MS plaques themselves.  Without exception, they were depleted.

Researchers led by I. Singh at the University of South Carolina examined the fundamental tissue abnormality in multiple sclerosis.  The actual myelin breakdown occurs to a large part because of the release of strong inflammatory chemicals called cytokines.  These cytokines generate huge numbers of free radicals.  Pre-treating neurological tissues with NAC (N-acetylcysteine) to raise glutathione levels protected these tissues from demyelination.  Conversely, when glutathione was chemically depleted the demyelination grew worse.

Simpler studies demonstrating decreased blood levels by glutathione peroxidase in MS patients have been repeated by many Scandinavian, Italian and North American researchers.  These levels as well can be inversely correlated with the degree of severity of the attack.

SELENIUM AND MULTPLE SCLEROSIS

Some research suggests that low selenium levels are connected to the development of MS.  Selenium is an essential part of the glutathione peroxidase enzyme and low selenium levels certainly decrease glutathione effectiveness.  A Danish team led by J. Mai supplied high-dose antioxidant supplements to MS patients made up of 6 mg selenium, 2 g vitamin C, and 480 mg of vitamin E.  These patients showed few side effects and glutathione peroxidase activity increased by a factor of five within five weeks.

Dr. Code Tells a compelling story of his diagnosis with multiple sclerosis and his personal journey to wellness.
Health Message with
Dr. William Code, MD, FRCPC

As Residency Program Director at the University of Saskatchewan, Dr. Code had a busy career of clinical work, research and teaching.  The Financial Post Fortune 500 Edition profiled him as the quintessential baby boomer when he left his hectic lifestyle for the quieter surroundings of Vancouver Island in 1992. 
Dr. Code added the treatment of chronic pain problems to his clinical anesthesia practice but soon after, began to notice major problems with foot drop, fatigue and increasing weakness of his right side.  Dr. Code tells a compelling story of his diagnosis with multiple sclerosis and his personal journey to wellness.
 
Dr. Code describes the development of a product that is destined to become the #1 nutritional supplement of choice worldwide and why the medical community should focus on nutritional-based, rather than drug-based interventions.

His recovery, as far as he is concerned, has been impacted by this product, a nutraceutical, cystine delivery system product, developed at McGill University Research Center by Dr. Gustavo Bounous.


What is your medical background?
I completed 13 years of medical training, which included 2 years of research on the brain.  This permitted me to be a specialist in anesthesiology in Canada and the United States.  My major interest within this field was pain management in long-term illnesses, such as multiple sclerosis, arthritis and fibromyalgia.

What is multiple sclerosis?
Multiple sclerosis is an autoimmune illness that strikes people most commonly in their 20’s, 30’s and 40’s.  It is now understood that MS results from some of our own white blood cells attacking the myelin (fatty) coating of the nerves in the brain and the spinal cord.

How long have you had multiple sclerosis?
I was diagnosed with multiple sclerosis in 1996.  At the time, I was stumbling when walking and I couldn’t empty a syringe with my right hand because it was so weak.  This, coupled with severe fatigue, necessitated that I leave my practice of anesthesiology and pain management.

What type of multiple sclerosis do you have?
I have been diagnosed with either primary progressive or secondary progressive multiple sclerosis by some of the best multiple sclerosis neurologists in North America.

Why do you use this product?
It helps optimize and smooth the function of our immune system.  It also helps by reducing the free radical injury to the myelin coating surrounding the nerves in the brain and the spinal cord.

How much do you take and how long was it before you noticed a difference?
I initially took a pack a day for three months and noticed no real difference.  I then spoke with a number of experts who suggested that I take three packs per day (2 at once and then another later on an empty stomach.) Apparently those of us with MS usually only have 5% of our optimal glutathione!  Within three to four weeks of increasing the amount as suggested, I noticed a big improvement in my energy and my cognitive function.

Does this product interfere with any of the drugs used in the treatment of multiple sclerosis or the symptoms of MS?
No, it does not.  In fact, in many cases, it might reduce the unpleasant side effects of agents such as interferon.

What has it done for you?
I know that it has greatly enhanced my energy levels and muscle strength.  It has almost eliminated the shooting electrical pains that are quite common among up to 70% of people with multiple sclerosis.  Certainly, the extra stamina has helped me regain my balance and position awareness (proprioception.)


Certainly, this product has been the largest piece of the puzzle in my recovery process. I recommend this product to all the people who want to stay healthy, to those folks facing health challenges and to my medical colleagues. If medical professionals will just take the time to research this product they will look at it differently than most alternative health products. 

Dr. Bill Code, MD, FRCPC

MS-Multiple sclerosis Testimonial:

I have a good friend who has been on this product next spring three years. She also will have been diagnosed with MS three years ago at the same time. She has been in remission ever since. In the winter actually uses their hot tub. And the summer before she took bike lessons and learned how to ride the Harley her and her husband bought. She works full time for the government and I know other then in the beginning she hasn’t been forced to lose any time at work because of it. She went through probably the most stressful time in her personal life as well as at work, and she came through with just a little numbness in her leg. Everyone with MS should be on this product, for that matter everyone should be on it. Debbie H. / Alberta, Canada

pagetop

MS-Multiple Sclerosis Testimonial:

My name is Karen. One morning in 1995, I woke up in the morning and fell to the floor –I had partial paralysis along my left side. At first, the doctors thought I had a stroke, but upon further investigation, the final diagnosis was probable Multiple Sclerosis. I was given intravenous steroids to reduce the swelling in my brain to give me back my mobility. But that was just the beginning. I was given Amitriptyline and Carbamazepine for reducing the pain and Dilantin to control seizures. My blood pressure went sky high (200/165) and I was given Atenol (and of course water pills to counteract the side effects of the Atenol). I was taking so many different drugs, I felt like a regular pharmacy. In 1996, I had another attack where I partially lost my sight. Everything was fuzzy like real bad reception on your T.V. This meant more drugs and two weeks in the hospital. After two years of all the pills and the various attacks, I was really worn out. I was suffering from total fatigue and couldn’t stay awake past 8 pm. Then in November 1997, I was introduced to this product. After only two weeks, I started to feel the difference. The pain was diminishing and before long I wasn’t taking any more pain killers. I also said goodbye to the blood pressure pills. BUT most of all, I have energy again and LOTS of it! I am able to do all the things I used to do before the MS. I got my life back–Thank You!  Karen lives in Toronto, Canada. She is available to speak with MS patients.

MS-Multiple Sclerosis Testimonial:

March 11, 2001, Hi my name is Beth M. I am from Peterborough, Ontario and I have Multiple Sclerosis (MS)  I am very happy to say that I am doing quite well with the help of this product I am not on any medication. I am getting really good strength in my legs back so I don’t need to take as many rest breaks. I feel that overall I am feeling a lot better and can deal with stressful situations a lot better. I admit I still have to pace myself. I can not clean the whole house in one afternoon but I can do room by room and that is more than I was doing 1 ½ years ago. My daughter who is five years old makes sure that I remember to take my two packs a day because she knows that it is helping her mommy. I am so happy to be able to do things on my own again and still ask for help the odd time. It is great to be able to drive again and have my vision clear. I can stand and not feel as dizzy (still a bit but not as much). I can walk through a crowd without feeling too dizzy. Last year at this time I was using a walker and I was not too strong at all. I do not ever want to be confined like that again and I thank God and Immunocal for helping me. Those of you who have MS please feel free to contact me if you would like to talk and those of you who don’t have MS just pray to God and thank him for keeping you from this disease. Thanks Immunotec for your help Beth M.

Glutathione as a dietary supplement.

We must first clarify an important, frequently misunderstood part of the glutathione story.

Upon learning about glutathione for the first time, many people go to their health store, buy it, and start dosing themselves. However, while glutathione is freely available in this form, this sort of oral, ingested glutathione will have negligible effects on your health. The product decomposes rapidly in the digestive system and is quickly removed from the gut. Apart from a few very specific instances, glutathione cannot be introduced into the body in this way. It must be made within your cells -which is where it’s naturally found. The effective way to stimulate the production of glutathione is to provide your body with the basic elements it needs to make glutathione by itself. Some pharmaceutical medications, such as N-acetyl-cysteine (NAC), have been developed to provide these precursors. There are also natural ways to increase glutathione levels, in particular the use of denatured (bioactive) whey proteins.

These are discussed throughout this website.

MS-Multiple Sclerosis Testimonial:

Dear Dr. Bounous,

I don’t know how to start a letter of such importance other than to just get started trying to tell you how much you have changed not only my life but that of my whole family. I had been diagnosed with Multiple Sclerosis over 20 years ago. I have relapsing remitting form of MS. I have gone the full gambit of symptoms over the years. Everything from numbness to paralysis, blurred vision to blindness and pain. I’m sure you can imagine how many drugs and therapies. I have never experienced a Christmas season without my yearly stay in hospital undergoing some form of IV therapy. This is my first year without visiting my local hospital. Approximately nine months ago after a month and a half in hospital I was introduced to this product by a good friend Sandra McCrindle. She sat in my kitchen with another distributor spouting all the praises of the product to my husband. I wouldn’t come out to listen. I had heard it all before. All I wanted to know is when I could take my next Morphine pill. The two dear friends persisted and my husband bought our first box . After much persuasion from my husband, I drank the drink he had mixed for me not expecting anything from it. After two months on the product, I had to admit that I was feeling better. Only after our daughter came home from Ottawa and was amazed in the difference she saw since she had last seen me in hospital did I really start to believe it. I was so stubborn even when I was up walking in my walker. I am now after ten months on the product not taking anything for pain or any other MS medication. I don’t use anything for walking in the house; and only use a cane outside for uneven ground.  My mother also has had MS for over 30 years. She is also having phenomenal results with the product. She has been on the product for over three months now and our family could not believe the change in either of us at Christmas. Her speech, and over all strength have dramatically improved. She is also free from bladder infections since on Immunocal. Although she is full time in a wheelchair her overall quality of life has improved. Her transfers are stronger; and she even stood up for the family at Christmas with little assistance. My husband after watching me improve so dramatically wanted to try the product also. He has Wegner granulomatosis and was going through a difficult time with side effects to chemo drugs like cyclophosphamide and other drugs. The product has improved his strength and he no longer has the nausea from side effects of the drugs he must continue to take. Our family is now a four box a month user. Even our dog Burt couldn’t be left out; so he is on Xtralife. My children and husband have their wife and mother back because of your research and talent in bringing this wonderful product to everyone. Thank you, Thank-you, Thank you. Our whole family is on Immunocal and feeling the benefits. Sincerely, Kathy Charlwood

pagetop

MS-Multiple sclerosis Testimonial:

“I started on this product in November 2000. I met someone on the internet, when we were talking once I mentioned that I have MS, her reply was “Me too, I have this nutritional product that you have to try”. She was kind enough to send me a months supply. I tried it and 6 days later I noticed a dramatic eradication of one of the MS symptom. For months before I had developed an extremely weak bladder causing me to be incontinent (wetting accidents) so often that I needed to wear bladder protection. This was a very disruptive symptom that had developed because of MS. Only 6 days after starting on the product I did not have that problem any longer. I still wore the bladder protection for about 2 weeks or so due to fear that it would return but every time I was forced to have to “hold it” I had not one drop of an accident. I no longer need to wear that protection. 6 months later I steadily have more improvements. The exhaustion I was experiencing has diminished to not noticeable. My vision and stability has also dramatically improved. I thank God for my friend for telling me of this incredible product . ” Sincerely, Dawn Turck  05/23/2001

 
Richard Jackan (Right) with
radio commentator Michael Reagan

MS-Multiple SclerosisTes timonial: 

My name is Richard J. I was diagnosed with multiple sclerosis in 1997 at that time I was the chief engineer of an electrical connector company in Santa Ana California. After several months the company decided I should retire so they gave me one year salary and a nice goodbye. I went from a very good salary to Social Security. Well that was the beginning of my quest to find some way to find relief from multiple sclerosis. Since that time I have looked into multiple forms of relief, I started out by going to anyone that seemed to have something they said would help, I went to several chiropractors and herbalists, I even tried Hyperbaric Medicine, which is going into a chamber which simulates you going underwater to 37 ft. and breathing pure oxygen while in the chamber, while I was doing the Hyperbaric Medicine, I found out about glutathione, which is an essential health aid, from a clinical nurse specialist who informed me that glutathione is only administered intravenously so I had him order a supply so he could administer it. So I started injecting glutathione and it really seemed to work on the symptoms of multiple sclerosis, I continued use it until I discontinued the Hyperbaric Medicine, which was too costly to maintain. I started looking for a new source of glutathione I looked throughout the Internet trying to find a new source for glutathione, I found many references to glutathione but the sources for glutathione were in pill form, and from my research I knew that glutathione does not work when taken orally. So I continued my search and bumped into a product that claimed it produced glutathione internally that product is Immunocal. I went into the Internet to locate sources for Immunocal and I got in contact with the Immunocal Company Representative and ordered my first boxes of Immunocal.
And now my story really begins. I started taking Immunocal on September 8, 2003 since that time I have started noticing a slow recuperation first after a couple of weeks the bottoms of my feet, which had very little feeling and my toes were not spreading when I wanted them to, both the feeling of the bottom of my feet has come back and I can spread my toes at will, which might not seem to impressive but when the feeling comes back and you can move your toes at will, that’s not bad. Another encouraging thing that has happened is after I came down with this little case of MS (Joke)… I was no longer able to snap the fingers of my left hand, interesting enough, after a few weeks of using Immunocal I was able, once again, to snap the fingers of my left hand and that’s also not bad. Other interesting things have been happening, I seem to have better vision and other things seem to be functioning better.”  
Richard J.

MS-Multiple Sclerosis Testimonial: Susan Doppler from North Dakota shared:    Hi, my name is Tom Paul and I am 45 years young. This is my story about Immunocal and how it has assisted us in our fight with Multiple Sclerosis (MS). In 1987 I began having various problems walking, standing, and with my vision. I went in to see my doctor and they indicated I had MS. I denied having the disease for about eight years, at which time it began to eliminate my ability to be independent in life i.e., could not walk without falling, very tired, vision problems. Ruby, my spouse and I determined it was time to begin to get serious about this MS. We adjusted my diet, and I began taking a multiple vitamin. This really did not seem to make much of a difference, and some friends suggested I talk with the Doppler’s regarding nutrition. Sue told me about Immunocal. I begin to use it and saw some benefits, but still was having complications due to the MS. Sue suggested that I raise my intake to two packets a day, I did and since then we’ve seen more improvement. We really believe that I am doing better because of our faith in God, a good attitude, diet, exercises, and Immunocal. I was in to see the doctor three weeks ago and they did a spinal tap and determined by the spinal fluid that the MS is in remission. This is the first time in three years there has been any improvement. We give the glory to God, the great supplements that the Doppler’s have introduced us to and a great attitude. Jesus is our life………Tom and Ruby Paul

Drugs NAC and OTC can raise glutathione levels, but their effects are short-lived. These pharmaceutical drugs also have little nutritional value. Whey proteins have excellent nutritional value but usually lack glutathione precursors. The ideal source of dietary cysteine should be natural, nutritional, bioactive, and undenatured and As many of you are aware, whey protein, especially whey protein isolates (over 90% protein), are sometimes referred to as the “perfect” proteins because they contain all the essential amino acids required for your body’s protein synthesis. With a biological value (BV) of over 110, it would be challenging to find a protein utilized more efficiently than Immunocal.

CONCLUSION

MS is a difficult disease to study because its spontaneous remissions and relapses make it very unpredictable.  It is therefore hard to correlate any sort of intervention with changes in a patient’s condition.  In order to be statistically significant, prospective trials would have to include hundreds of subjects.

However, certain findings have been demonstrated consistently in multiple sclerosis patients.  The breakdown products of oxidative stress are present in large numbers, and the level of free radical formation corresponds to the severity of the MS attack.  Furthermore, glutathione activity is clearly impaired in this disease.

Also, individual tissues suffer less free radical damage when antioxidants and glutathione therapy are used.  Although not a cure, many authors have suggested that reduced oxidative damage would help MS patients, and suggest in particular the helpful role of elevated glutathione levels.

REFERENCES TO MULTIPLE SCLEROSIS

CALABRESE V, RAFFAELE R, COSENTINO E, RIZZA V.  Changes in cerebrospinal fluid levels of malondialdehyde and GSH reductase activity in multiple sclerosis.  International Journal of Clinical Pharmacology Research 14(4):119-123, 1994

CLAUSEN J, JENSEN GE, NIELSEN SA.  Selenium in chronic neurologic diseases.  Multiple sclerosis and Batten’s disease.  Biological Trace Element Research 15:179-203, 1988

GUY J, ELLIS EA, HOPE GM, RAO NA.  Antioxidant enzymes reduce loss of blood-brain barrier integrity in experimental optic neuritis.  Archives of Ophthalmology 107(9):1359-63 1989

JENNER P.  Oxidative damage in neurodegenerative disease.  Lancet 344:796-798, 1994

JENSEN GE, CLAUSEN J.  Glutathione peroxidase and reductase, glucose-6-phosphate dehydrogenase and catalase activities in multiple sclerosis.  J. Neurol. Sci. 63:45-53, 1984

KARG E, KLIVENYI P, NEMETH I, ET AL.  Nonenzymatic antioxidants of blood in multiple sclerosis.  J. Neurol. 246:533-539, 1999

KNIGHT JA.  Reactive oxygen species and the neurodegenerative disorders.  Annuals of Clinical Laboratory Science 27(1):11-25, 1997

The use of glutathione supplementation fights all kind of diseases from respiratory to auto immune to degenerative diseases.

Without question, the best type of preventive medicine is an optimized immune system, and a critical means to optimize it is by feeding it glutathione.

This is not the same glutathione that you see at the health food store. This is glutathione precursor. It’s very different because glutathione must be made inside your cells and the precursor is the food your cells   require to make its own glutathione as nature intended. That is the most natural and effective approach to boost your immune system.

It’s all natural with NO side effect. 

Want to know if this is for you? 

You can try it for only $10.00 (5-day sample)

Just send me a text here 703-895-0496 with the hashtag “sample” and I will send you a form to fill out, so I know where to send it.

Feel Normal Again!